Human FUCA1 activation kit by CRISPRa

CAT#: GA101668

FUCA1 CRISPRa kit - CRISPR gene activation of human alpha-L-fucosidase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FUCA1
• Locus ID: 2517
• Kit Components:

  GA101668G1, FUCA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101668G2, FUCA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101668G3, FUCA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000147
• Synonyms: FUCA
• Summary: 'The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.[provided by RefSeq, Oct 2009]'