Human Frizzled 2 (FZD2) activation kit by CRISPRa

CAT#: GA101684

FZD2 CRISPRa kit - CRISPR gene activation of human frizzled class receptor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FZD2
• Locus ID: 2535
• Kit Components:

  GA101684G1, Frizzled 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101684G2, Frizzled 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101684G3, Frizzled 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001466
• Synonyms: fz-2; Fz2; fzE2; hFz2
• Summary: 'This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010]'