Human GABA A Receptor beta 2 (GABRB2) activation kit by CRISPRa

CAT#: GA101704

GABRB2 CRISPRa kit - CRISPR gene activation of human gamma-aminobutyric acid type A receptor beta2 subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GABRB2
• Locus ID: 2561
• Kit Components:

  GA101704G1, GABA A Receptor beta 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101704G2, GABA A Receptor beta 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101704G3, GABA A Receptor beta 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000813, NM_021911
• Synonyms: MGC119386; MGC119388; MGC119389
• Summary: 'The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008]'