Human GABRR1 activation kit by CRISPRa

CAT#: GA101712

GABRR1 CRISPRa kit - CRISPR gene activation of human gamma-aminobutyric acid type A receptor rho1 subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GABRR1
• Locus ID: 2569
• Kit Components:

  GA101712G1, GABRR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101712G2, GABRR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101712G3, GABRR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256703, NM_001256704, NM_001256705, NM_001267582, NM_002042
• Summary: 'GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]'