Human KAT2A activation kit by CRISPRa

CAT#: GA101767

KAT2A CRISPRa kit - CRISPR gene activation of human lysine acetyltransferase 2A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KAT2A
• Locus ID: 2648
• Kit Components:

  GA101767G1, KAT2A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101767G2, KAT2A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101767G3, KAT2A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021078
• Synonyms: GCN5; GCN5L2; hGCN5; PCAF-b
• Summary: 'KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009]'