Human Glycerol kinase (GK) activation kit by CRISPRa

CAT#: GA101812

GK CRISPRa kit - CRISPR gene activation of human glycerol kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GK
• Locus ID: 2710
• Kit Components:

  GA101812G1, Glycerol kinase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101812G2, Glycerol kinase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101812G3, Glycerol kinase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000167, NM_001128127, NM_001205019, NM_203391
• Synonyms: GK1; GKD
• Summary: 'The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]'