Human alpha 1 Glycine Receptor (GLRA1) activation kit by CRISPRa

CAT#: GA101828

GLRA1 CRISPRa kit - CRISPR gene activation of human glycine receptor alpha 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GLRA1
• Locus ID: 2741
• Kit Components:

  GA101828G1, alpha 1 Glycine Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101828G2, alpha 1 Glycine Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101828G3, alpha 1 Glycine Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000171, NM_001146040, NM_001292000
• Synonyms: HKPX1; STHE
• Summary: 'The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript variants encoding different isoforms have been found. [provided by RefSeq, Dec 2015]'