Human GNS activation kit by CRISPRa

CAT#: GA101869

GNS CRISPRa kit - CRISPR gene activation of human glucosamine (N-acetyl)-6-sulfatase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GNS
• Locus ID: 2799
• Kit Components:

  GA101869G1, GNS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101869G2, GNS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101869G3, GNS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002076
• Synonyms: G6S
• Summary: 'The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq, Jul 2008]'