Human GPX5 activation kit by CRISPRa

CAT#: GA101939

GPX5 CRISPRa kit - CRISPR gene activation of human glutathione peroxidase 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPX5
• Locus ID: 2880
• Kit Components:

  GA101939G1, GPX5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101939G2, GPX5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101939G3, GPX5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001509, NM_003996, NR_144470
• Synonyms: HEL-S-75p
• Summary: 'This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike several other characterized glutathione peroxidases, this enzyme is not a selenoprotein, lacking the selenocysteine residue. Thus, it is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2016]'