Human GSK3 alpha (GSK3A) activation kit by CRISPRa

CAT#: GA101982

GSK3A CRISPRa kit - CRISPR gene activation of human glycogen synthase kinase 3 alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GSK3A
• Locus ID: 2931
• Kit Components:

  GA101982G1, GSK3 alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101982G2, GSK3 alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101982G3, GSK3 alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019884
• Synonyms: DKFZp686D0638
• Summary: 'This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011]'