Human TFIIE beta (GTF2E2) activation kit by CRISPRa

CAT#: GA102006

GTF2E2 CRISPRa kit - CRISPR gene activation of human general transcription factor IIE subunit 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GTF2E2
• Locus ID: 2961
• Kit Components:

  GA102006G1, TFIIE beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102006G2, TFIIE beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102006G3, TFIIE beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002095, NM_001348353
• Synonyms: FE; TF2E2; TFIIE-B
• Summary: 'The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by this gene represents the beta subunit of TFIIE. [provided by RefSeq, Jan 2017]'