Human GTF2H3 activation kit by CRISPRa

CAT#: GA102011

GTF2H3 CRISPRa kit - CRISPR gene activation of human general transcription factor IIH subunit 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GTF2H3
• Locus ID: 2967
• Kit Components:

  GA102011G1, GTF2H3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102011G2, GTF2H3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102011G3, GTF2H3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271866, NM_001271867, NM_001271868, NM_001516
• Synonyms: BTF2; P34; TFB4; TFIIH
• Summary: 'This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012]'