Human BRF1 activation kit by CRISPRa

CAT#: GA102015

BRF1 CRISPRa kit - CRISPR gene activation of human BRF1 RNA polymerase III transcription initiation factor subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BRF1
• Locus ID: 2972
• Kit Components:

  GA102015G1, BRF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102015G2, BRF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102015G3, BRF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242786, NM_001242787, NM_001242788, NM_001242789, NM_001242790, NM_001519, NM_145685, NM_145696, N91109
• Synonyms: BRF; BRF-1; CFDS; GTF3B; hBRF; HEL-S-76p; TAF3B2; TAF3C; TAFIII90; TF3B90; TFIIIB90
• Summary: 'This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq, Jun 2011]'