Human GCAP1 (GUCA1A) activation kit by CRISPRa

CAT#: GA102019

GUCA1A CRISPRa kit - CRISPR gene activation of human guanylate cyclase activator 1A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GUCA1A
• Locus ID: 2978
• Kit Components:

  GA102019G1, GCAP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102019G2, GCAP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102019G3, GCAP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000409, NM_001319061, NM_001319062
• Synonyms: C6orf131; COD3; CORD14; GCAP; GCAP1; GUCA; GUCA1
• Summary: 'This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. provided by RefSeq, Jul 2020]'