Human GUCY2C activation kit by CRISPRa

CAT#: GA102025

GUCY2C CRISPRa kit - CRISPR gene activation of human guanylate cyclase 2C

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GUCY2C
• Locus ID: 2984
• Kit Components:

  GA102025G1, GUCY2C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102025G2, GUCY2C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102025G3, GUCY2C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004963
• Synonyms: DIAR6; GUC2C; MECIL; MUCIL; STAR
• Summary: 'This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]'