Human HABP2 activation kit by CRISPRa

CAT#: GA102058

HABP2 CRISPRa kit - CRISPR gene activation of human hyaluronan binding protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HABP2
• Locus ID: 3026
• Kit Components:

  GA102058G1, HABP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102058G2, HABP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102058G3, HABP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001177660, NM_004132
• Synonyms: FSAP; HABP; HGFAL; NMTC5; PHBP
• Summary: 'This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]'