Human HMG14 (HMGN1) activation kit by CRISPRa

CAT#: GA102148

HMGN1 CRISPRa kit - CRISPR gene activation of human high mobility group nucleosome binding domain 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HMGN1
• Locus ID: 3150
• Kit Components:

  GA102148G1, HMG14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102148G2, HMG14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102148G3, HMG14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004965
• Synonyms: HMG14
• Summary: 'The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes. [provided by RefSeq, Aug 2011]'