Human HOXA1 activation kit by CRISPRa

CAT#: GA102183

HOXA1 CRISPRa kit - CRISPR gene activation of human homeobox A1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HOXA1
• Locus ID: 3198
• Kit Components:

  GA102183G1, HOXA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102183G2, HOXA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102183G3, HOXA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005522, NM_153620
• Synonyms: BSAS; HOX1; HOX1F
• Summary: 'In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region. [provided by RefSeq, Jul 2008]'