Human HOXA10 activation kit by CRISPRa

CAT#: GA102191

HOXA10 CRISPRa kit - CRISPR gene activation of human homeobox A10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HOXA10
• Locus ID: 3206
• Kit Components:

  GA102191G1, HOXA10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102191G2, HOXA10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102191G3, HOXA10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018951, NM_153715, NR_037939
• Synonyms: HOX1; HOX1.8; HOX1H; PL
• Summary: 'In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene. [provided by RefSeq, Mar 2011]'