Human HOXB5 activation kit by CRISPRa

CAT#: GA102199

HOXB5 CRISPRa kit - CRISPR gene activation of human homeobox B5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HOXB5
• Locus ID: 3215
• Kit Components:

  GA102199G1, HOXB5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102199G2, HOXB5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102199G3, HOXB5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002147
• Synonyms: HHO.C10; HOX2; Hox2.1; HOX2A; HU-1
• Summary: 'This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008]'