Human HRH2 activation kit by CRISPRa

CAT#: GA102238

HRH2 CRISPRa kit - CRISPR gene activation of human histamine receptor H2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HRH2
• Locus ID: 3274
• Kit Components:

  GA102238G1, HRH2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102238G2, HRH2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102238G3, HRH2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001131055, NM_022304, NR_160284, NM_001367711
• Synonyms: H2R
• Summary: 'Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]'