Human ID2 activation kit by CRISPRa

CAT#: GA102306

ID2 CRISPRa kit - CRISPR gene activation of human inhibitor of DNA binding 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ID2
• Locus ID: 3398
• Kit Components:

  GA102306G1, ID2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102306G2, ID2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102306G3, ID2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002166
• Synonyms: bHLHb26; GIG8; ID2A; ID2H
• Summary: 'The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Aug 2011]'