Human IKK beta (IKBKB) activation kit by CRISPRa

CAT#: GA102370

IKBKB CRISPRa kit - CRISPR gene activation of human inhibitor of nuclear factor kappa B kinase subunit beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IKBKB
• Locus ID: 3551
• Kit Components:

  GA102370G1, IKK beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102370G2, IKK beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102370G3, IKK beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190720, NM_001190721, NM_001190722, NM_001242778, NM_001556, NR_033818, NR_033819, NR_033820, NR_040009
• Synonyms: IKK-beta; IKK2; IKKB; IMD15; NFKBIKB
• Summary: 'The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011]'