Human IL2 Receptor gamma (IL2RG) activation kit by CRISPRa

CAT#: GA102379

IL2RG CRISPRa kit - CRISPR gene activation of human interleukin 2 receptor subunit gamma

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL2RG
• Locus ID: 3561
• Kit Components:

  GA102379G1, IL2 Receptor gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102379G2, IL2 Receptor gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102379G3, IL2 Receptor gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000206
• Synonyms: CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1
• Summary: 'The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010]'