Human Integrin alpha 1 (ITGA1) activation kit by CRISPRa

CAT#: GA102463

ITGA1 CRISPRa kit - CRISPR gene activation of human integrin subunit alpha 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ITGA1
• Locus ID: 3672
• Kit Components:

  GA102463G1, Integrin alpha 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102463G2, Integrin alpha 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102463G3, Integrin alpha 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_181501
• Synonyms: CD49a; VLA1
• Summary: 'This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]'