Human ITK activation kit by CRISPRa

CAT#: GA102490

ITK CRISPRa kit - CRISPR gene activation of human IL2 inducible T cell kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ITK
• Locus ID: 3702
• Kit Components:

  GA102490G1, ITK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102490G2, ITK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102490G3, ITK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005546
• Synonyms: EMT; LPFS1; LYK; PSCTK2
• Summary: 'This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008]'