Human KCNC4 activation kit by CRISPRa

CAT#: GA102525

KCNC4 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily C member 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNC4
• Locus ID: 3749
• Kit Components:

  GA102525G1, KCNC4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102525G2, KCNC4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102525G3, KCNC4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039574, NM_004978, NM_153763, NR_036437
• Synonyms: C1orf30; HKSHIIIC; KSHIIIC; KV3.4
• Summary: 'The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]'