Human KCND1 activation kit by CRISPRa

CAT#: GA102526

KCND1 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily D member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCND1
• Locus ID: 3750
• Kit Components:

  GA102526G1, KCND1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102526G2, KCND1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102526G3, KCND1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004979
• Synonyms: KV4.1
• Summary: 'This gene encodes a multipass membrane protein that comprises the pore subunit of the voltage-gated A-type potassium channel, which functions in the repolarization of membrane action potentials. Activity of voltage-gated potassium channels is important in a number of physiological processes, among them the regulation of neurotransmitter release, heart rate, insulin secretion, and smooth muscle contraction. [provided by RefSeq, Aug 2013]'