Human Kir7.1 (KCNJ13) activation kit by CRISPRa

CAT#: GA102545

KCNJ13 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily J member 13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNJ13
• Locus ID: 3769
• Kit Components:

  GA102545G1, Kir7.1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102545G2, Kir7.1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102545G3, Kir7.1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001172416, NM_001172417, NM_002242
• Synonyms: KIR1.4; KIR7.1; LCA16; SVD
• Summary: 'This gene encodes a member of the inwardly rectifying potassium channel family of proteins. Members of this family form ion channel pores that allow potassium ions to pass into a cell. The encoded protein belongs to a subfamily of low signal channel conductance proteins that have a low dependence on potassium concentration. Mutations in this gene are associated with snowflake vitreoretinal degeneration. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]'