Human KCNS3 activation kit by CRISPRa

CAT#: GA102563

KCNS3 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel modifier subfamily S member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNS3
• Locus ID: 3790
• Kit Components:

  GA102563G1, KCNS3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102563G2, KCNS3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102563G3, KCNS3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282428, NM_002252
• Synonyms: KV9.3
• Summary: 'Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013]'