Human LCT activation kit by CRISPRa

CAT#: GA102671

LCT CRISPRa kit - CRISPR gene activation of human lactase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LCT
• Locus ID: 3938
• Kit Components:

  GA102671G1, LCT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102671G2, LCT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102671G3, LCT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002299
• Synonyms: LAC; LPH; LPH1
• Summary: 'The protein encoded by this gene belongs to the glycosyl hydrolase 1 family of proteins. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme is integral to the plasma membrane and has both phlorizin hydrolase activity and lactase activity. Mutations in this gene are associated with congenital lactase deficiency. Polymorphisms in this gene are associated with lactase persistence, in which intestinal lactase activity persists at childhood levels into adulthood. [provided by RefSeq, Jan 2016]'