Human Hormone sensitive lipase (LIPE) activation kit by CRISPRa

CAT#: GA102705

LIPE CRISPRa kit - CRISPR gene activation of human lipase E, hormone sensitive type

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LIPE
• Locus ID: 3991
• Kit Components:

  GA102705G1, Hormone sensitive lipase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102705G2, Hormone sensitive lipase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102705G3, Hormone sensitive lipase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005357
• Synonyms: AOMS4; FPLD6; HSL; LHS
• Summary: 'The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. [provided by RefSeq, Jul 2008]'