Human LSS activation kit by CRISPRa

CAT#: GA102741

LSS CRISPRa kit - CRISPR gene activation of human lanosterol synthase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LSS
• Locus ID: 4047
• Kit Components:

  GA102741G1, LSS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102741G2, LSS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102741G3, LSS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001438, NM_001145436, NM_001145437, NM_002340
• Synonyms: OSC
• Summary: 'The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]'