Human MAK activation kit by CRISPRa

CAT#: GA102801

MAK CRISPRa kit - CRISPR gene activation of human male germ cell associated kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAK
• Locus ID: 4117
• Kit Components:

  GA102801G1, MAK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102801G2, MAK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102801G3, MAK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242385, NM_001242957, NM_005906, NR_134935, NR_134936
• Synonyms: dJ417M14.2; RP62
• Summary: 'The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene have been associated with ciliary defects resulting in retinitis pigmentosa 62. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]'