Human Mannosidase II (MAN2A1) activation kit by CRISPRa

CAT#: GA102806

MAN2A1 CRISPRa kit - CRISPR gene activation of human mannosidase alpha class 2A member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAN2A1
• Locus ID: 4124
• Kit Components:

  GA102806G1, Mannosidase II gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102806G2, Mannosidase II gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102806G3, Mannosidase II gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002372
• Synonyms: AMan II; GOLIM7; MANA2; MANII
• Summary: 'This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq, Dec 2013]'