Human ME1 activation kit by CRISPRa

CAT#: GA102860

ME1 CRISPRa kit - CRISPR gene activation of human malic enzyme 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ME1
• Locus ID: 4199
• Kit Components:

  GA102860G1, ME1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102860G2, ME1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102860G3, ME1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002395
• Synonyms: HUMNDME; MES
• Summary: 'This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008]'