Human Menin (MEN1) activation kit by CRISPRa

CAT#: GA102876

MEN1 CRISPRa kit - CRISPR gene activation of human menin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MEN1
• Locus ID: 4221
• Kit Components:

  GA102876G1, Menin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102876G2, Menin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102876G3, Menin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000244, NM_130799, NM_130800, NM_130801, NM_130802, NM_130803, NM_130804, NM_001370259, NM_001370261, NM_001370262, NM_001370251, NM_001370260, NM_001370263
• Synonyms: MEAI; SCG2
• Summary: 'This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic gene regulation. It is thought to regulate several pathways and processes by altering chromatin structure through the modification of histones. [provided by RefSeq, May 2019]'