Human CTAGE5 (MIA2) activation kit by CRISPRa

CAT#: GA102898

MIA2 CRISPRa kit - CRISPR gene activation of human MIA SH3 domain ER export factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MIA2
• Locus ID: 4253
• Kit Components:

  GA102898G1, CTAGE5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102898G2, CTAGE5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102898G3, CTAGE5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001247988, NM_001247989, NM_001247990, NM_005930, NM_054024, NM_203354, NM_203355, NM_203356, NM_203357, NM_001329214, NM_001354137, NM_001354138, NM_001354139, NM_001354140, NM_001354141, NM_001354142, NM_001354143, NM_001354144, NM_001354145, NM_001354146, NM_001354147, NM_001354148, NM_001354149, NM_001354150, NM_001354151, NM_001354152, NM_001354153, NM_001354154, NM_001354155, NM_001354156, NM_001354157, NR_148721, NR_148722, NR_148723
• Synonyms: MEA6; MGEA; MGEA6; MGEA11
• Summary: 'This gene encodes s receptor in the endoplasmic reticulum, which plays a role in the export of large pre-chylomicrons and pre-very low density lipoproteins (pre-VLDLs). Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts, cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species (TANGO1-like or TALI). Additionally, alternative splicing in these transcripts results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Sep 2016]'