Human MUC7 activation kit by CRISPRa

CAT#: GA103038

MUC7 CRISPRa kit - CRISPR gene activation of human mucin 7, secreted

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MUC7
• Locus ID: 4589
• Kit Components:

  GA103038G1, MUC7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103038G2, MUC7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103038G3, MUC7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145006, NM_001145007, NM_152291
• Synonyms: MG2
• Summary: 'This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. This antimicrobial protein has antibacterial and antifungal activity. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Oct 2014]'