Human MYBPC1 activation kit by CRISPRa

CAT#: GA103050

MYBPC1 CRISPRa kit - CRISPR gene activation of human myosin binding protein C, slow type

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MYBPC1
• Locus ID: 4604
• Kit Components:

  GA103050G1, MYBPC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103050G2, MYBPC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103050G3, MYBPC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001254718, NM_001254719, NM_001254720, NM_001254721, NM_001254722, NM_001254723, NM_002465, NM_206819, NM_206820, NM_206821
• Synonyms: LCCS4; MYBPCC; MYBPCS
• Summary: 'This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]'