Human Nck (NCK1) activation kit by CRISPRa

CAT#: GA103120

NCK1 CRISPRa kit - CRISPR gene activation of human NCK adaptor protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NCK1
• Locus ID: 4690
• Kit Components:

  GA103120G1, Nck gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103120G2, Nck gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103120G3, Nck gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190796, NM_001291999, NM_006153
• Synonyms: NCK; nck-1; NCKalpha
• Summary: 'The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010]'