Human NDUFA8 activation kit by CRISPRa

CAT#: GA103131

NDUFA8 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase subunit A8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NDUFA8
• Locus ID: 4702
• Kit Components:

  GA103131G1, NDUFA8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103131G2, NDUFA8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103131G3, NDUFA8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001318195, NM_014222
• Synonyms: CI-19KD; CI-PGIV; PGIV
• Summary: 'The protein encoded by this gene belongs to the complex I 19 kDa subunit family. Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays an important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]'