Human NDUFB6 activation kit by CRISPRa

CAT#: GA103141

NDUFB6 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase subunit B6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NDUFB6
• Locus ID: 4712
• Kit Components:

  GA103141G1, NDUFB6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103141G2, NDUFB6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103141G3, NDUFB6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199987, NM_002493, NM_182739
• Synonyms: B17; CI
• Summary: 'The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jan 2011]'