Human NDUFS8 activation kit by CRISPRa

CAT#: GA103155

NDUFS8 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase core subunit S8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NDUFS8
• Locus ID: 4728
• Kit Components:

  GA103155G1, NDUFS8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103155G2, NDUFS8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103155G3, NDUFS8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002496
• Synonyms: CI-23k; CI23KD; TYKY
• Summary: 'This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq, Mar 2010]'