Human HEF1 (NEDD9) activation kit by CRISPRa

CAT#: GA103163

NEDD9 CRISPRa kit - CRISPR gene activation of human neural precursor cell expressed, developmentally down-regulated 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NEDD9
• Locus ID: 4739
• Kit Components:

  GA103163G1, HEF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103163G2, HEF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103163G3, HEF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142393, NM_001271033, NM_006403, NM_182966, NR_073131
• Synonyms: CAS-L; CAS2; CASL; CASS2; HEF1
• Summary: 'The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]'