Human NELL2 activation kit by CRISPRa

CAT#: GA103171

NELL2 CRISPRa kit - CRISPR gene activation of human neural EGFL like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NELL2
• Locus ID: 4753
• Kit Components:

  GA103171G1, NELL2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA103171G2, NELL2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA103171G3, NELL2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145107, NM_001145108, NM_001145109, NM_001145110, NM_006159
• Synonyms: NRP2
• Summary: The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq, Feb 2009]