Human eNOS (NOS3) activation kit by CRISPRa

CAT#: GA103234

NOS3 CRISPRa kit - CRISPR gene activation of human nitric oxide synthase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NOS3
• Locus ID: 4846
• Kit Components:

  GA103234G1, eNOS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103234G2, eNOS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103234G3, eNOS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000603, NM_001160109, NM_001160110, NM_001160111
• Synonyms: ECNOS; eNOS
• Summary: 'Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]'