Human CNOT4 activation kit by CRISPRa

CAT#: GA103237

CNOT4 CRISPRa kit - CRISPR gene activation of human CCR4-NOT transcription complex subunit 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CNOT4
• Locus ID: 4850
• Kit Components:

  GA103237G1, CNOT4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103237G2, CNOT4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103237G3, CNOT4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001008225, NM_001190847, NM_001190848, NM_001190849, NM_001190850, NM_013316
• Synonyms: CLONE243; NOT4; NOT4H
• Summary: 'The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]'