Human P2X1 (P2RX1) activation kit by CRISPRa

CAT#: GA103352

P2RX1 CRISPRa kit - CRISPR gene activation of human purinergic receptor P2X 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: P2RX1
• Locus ID: 5023
• Kit Components:

  GA103352G1, P2RX1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA103352G2, P2RX1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA103352G3, P2RX1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002558
• Synonyms: P2X1
• Summary: The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013]