Human P2RX4 activation kit by CRISPRa

CAT#: GA103354

P2RX4 CRISPRa kit - CRISPR gene activation of human purinergic receptor P2X 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: P2RX4
• Locus ID: 5025
• Kit Components:

  GA103354G1, P2RX4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA103354G2, P2RX4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA103354G3, P2RX4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256796, NM_001261397, NM_001261398, NM_002560, NM_175567, NM_175568, NR_046372, NR_046373
• Synonyms: P2X4; P2X4R
• Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]